Cytoplasmic Transfer

Cytoplasm transplantation is a special assisted reproductive method developed to improve egg quality. In this process, the cytoplasm (intracellular fluid) of the egg cell taken from a young and healthy donor is injected into the expectant mother’s own egg just before the fertilization process takes place in the laboratory. This intracellular aspirate (liquid), called ooplasm, contains auxiliary organelles such as mitochondria, ribosomes, etc. In particular, mitochondria increase the fertilization capacity and the potential of the fertilized egg to reach the 5th day due to the mRNA it contains. This procedure helps to eliminate the defects of the patient’s egg associated with any metabolic disorders, and leads to the restoration of successful pregnancy and development of the embryo.

Cytoplasmic Transfer Is Suitable For:

  • Patients with reduced ovarian reserve

  • Patients with low egg quality

  • Couples who have previously experienced unsuccessful IVF attempts

  • Patients with good egg reserve but recurrent miscarriages

  • Women planning pregnancy at an advanced age

A small amount of cytoplasm is extracted from the young donor’s egg. This cytoplasm is injected into the cytoplasm of the patient’s egg, and then it is fertilized with sperm and transferred to the patient’s uterus. Fertilization results in a hybrid egg containing nuclear DNA from both biological parents.

Egg Donation may be recommended in cases of:

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With cytoplasmic transfer, the fertilization potential of the expectant mother’s egg is increased. At the same time, the fertilized egg, that is, the embryo, formed as a result of this process, has a higher potential to attach to the uterus. Thus, the pregnancy rate and the possibility of giving birth to a healthy child are increased.